METHOD FOR COATING AND DRYING HETEROGENOUS STEM CELL DERIVED EXTRA-CELLULAR VESICLES
Coated and Dried extracellular vesicles (EVs) represent an ideal method for preservation and increasing the shelf lifetime of the invention making it ready to use on time and on variety of species overcoming the previous challenges on isolation and preservation and undesirable immune responses. The invention compromises a coated freeze dried stem cells derived EVs that are ready for use to Stimulate/accelerate healing of soft/hard tissues, can be reconstituted in multiple forms and shapes and stimulated by Laser. The nature of the invention is a heterogenous and/or Xenogenous EVs which can overcome the challenges of individual and /or species diseases and immune reactions.
This invention relates to a method of coating and preserving extra cellular vesicles(EVs) obtained from stem cells of heterogenous donors, facilitating the pharmaceutical manufacturing and transportationand making them ready to use.
Heterogenicity of the product refers primarily to EVs obtained from different sources/donors (human, animal, birds, eggs, primary embryonic cells), not only to different type/sizes of cells or vesicles naturally existing in extracellular solutions. Xenogenousrefers to using the heterogenic product on recipient of another species/genus.
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EVs perform the same work as the cells of origin and as efficiently as the freshly prepared one despite being dehydrated.
Stimulate/accelerate healing of soft/hard tissues for example, treat skin problems/wounds, heart problems, musculoskeletal degenerative disorders, hepatic and renal degenerative disorders, immune stimulation/modulation and tissue grafts.
Can be used for studies in vivo and in vitro for evaluation of biological experiments like cell signaling, proteomics, cellular proliferation etc.
Does not generate an immune reaction.
Industries where the invention can be useful?
AutomobileAn estimate of the total addressable market?
5 MillionPotential Customers/End Users. Who might benefit?
ManufacturingActions
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Country | Current Status | Patent Application Number | Patent Number | Applicant / Current Assignee Name | Title | Google Patent Link |
India | Pending | 2019111752 | 2019111752 | ELTOOKHY, Omar Mohamed Salah Eldin Ahmed | METHOD FOR COATING AND DRYING HETEROGENOUS STEM CELL DERIVED EXTRA-CELLULAR VESICLES | Google patent link |
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